Phodaco 15 Dacomitinib

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  • Brand Name:
    Phodaco 15
  • Origin:
    Generic drug,Laos
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    Small batches also available
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  • Treatment
    EGFR exon 19 deletion of exon 21 L858R substitution non small cell lung cancer(NSCLC)
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    Phodaco 15
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Dacomitinib, sold under the brand name Phodaco15, Vizimpro, is a medication for the treatment of non-small-cell lung carcinoma (NSCLC). It is a selective and irreversible inhibitor of EGFR.

Dacomitinib has advanced to several Phase III clinical trials.[when?] The January 2014 results of the first trials were disappointing, with a failure to meet the study goals.Additional Phase III trials are ongoing.

In 2017, results of a trial comparing dacomitinib to gefitinib for NSCLC (driven by mutated EGFR) were announced.

Dacomitinib was approved for medical use in the United States in September 2018,in Japan in 2019, and in the European Union in 2019,for the treatment of non-small cell lung cancer with epidermal growth factor receptor (EGFR) gene mutation.

Why is this medication prescribed?
Dacomitinib is used to treat a certain type of non-small-cell lung cancer (NSCLC) that has spread to other parts of the body. Dacomitinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.

How should this medicine be used?
Dacomitinib comes as a tablet to take by mouth. It is usually taken once daily with or without food. Take dacomitinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dacomitinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you vomit after you take dacomitinib, do not immediately take another dose. Continue your regular dosing schedule.

Your doctor may temporarily or permanently stop your treatment or decrease your dose if you experience certain side effects of dacomitinib. Tell your doctor how you are feeling during your treatment. Continue to take dacomitinib even if you feel well. Do not stop taking dacomitinib without talking to your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What side effects can this medication cause?
Dacomitinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
weight loss
loss of appetite
mouth sores
infection of the skin around the fingernails or toenails
hair loss
lack of energy
difficulty falling asleep or staying asleep
red or swollen eyes ("pink eye")
taste changes