Molavir (Molnupiravir)

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    200MG/c, 21c/Bottle
  • Manufacturer
    Tongmeng (Lao) Pharmaceutical & Food Co., Ltd.

Molnupiravir is an antiviral medication that inhibits the replication of certain RNA viruses. It is used to treat COVID-19 in those infected by SARS-CoV-2.

Molnupiravir is a prodrug of the synthetic nucleoside derivative N4-hydroxycytidine and exerts its antiviral action through introduction of copying errors during viral RNA replication.

Molnupiravir was originally developed to treat influenza at Emory University by the university's drug innovation company, Drug Innovation Ventures at Emory (DRIVE), but was reportedly abandoned for mutagenicity concerns. It was then acquired by Miami-based company Ridgeback Biotherapeutics, which later partnered with Merck & Co. to develop the drug further.

Based on positive results in placebo-controlled double-blind randomized clinical trials, Molnupiravir was approved for medical use in the United Kingdom in November 2021.In December 2021, the U.S. Food and Drug Administration (FDA) granted an emergency use authorization (EUA) to molnupiravir for use in certain populations where other treatments are not feasible.[8] The emergency use authorization was only narrowly approved (13-10) because of questions regarding efficacy and concerns that molnupiravir's mutagenic effects could create new variants that evade immunity and prolong the COVID-19 pandemic.

Medical uses
Molnupiravir is indicated for the treatment of mild-to-moderate coronavirus disease (COVID-19) in adults with positive results of direct SARS-CoV-2 viral testing, and who are at high risk for progression to severe COVID-19.

Why is this medication prescribed?
Molnupiravir is used to treat coronavirus disease 2019 (COVID-19 infection) caused by the SARS-CoV-2 virus in adults who have mild to moderate symptoms and are at risk of severe disease that could result in hospitalization or death when other treatments are either not available or cannot be used. Molnupiravir is in a class of medications called antivirals. It works by stopping the virus from spreading in the body..

How should this medicine be used?
Molnupiravir comes as a capsule to take by mouth. It is usually taken with or without food two times a day for 5 days. Take molnupiravir at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take molnupiravir exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the capsules whole; do not split, chew, or crush them.

Take molnupiravir until you finish the prescription, even if you start to feel better. Do not stop taking molnupiravir without talking to your doctor. If you feel worse or develop new symptoms while taking molnupiravir, or if your COVID-19 symptoms do not start to get better, call your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

What side effects can this medication cause?
Molnupiravir may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Molnupiravir may alter bone or cartilage growth in children and is not recommended for people less than 18 years of age. Talk to your doctor about the risks of taking this medication.

Molnupiravir may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.