Contents hide 1 Larotrectinib 2 ADULT 2.1 Dosage Forms & Strengths 2.1.1 capsule 2.1.2 oral solution 2.2 Solid Tumors 2.3 Dosage Modifications 2.3.1 Dosage modifications for adverse reactions 2.3.1.1 Body Surface Area (BSA) ≥1 m2 2.3.2 Grade ≥3 adverse reactions 2.3.3 Strong CYP3A4 inhibitors 2.3.4 Strong CYP3A4 inducers 2.3.5 Hepatic impairment 2.3.6 Renal impairment 2.4 Dosing Considerations 2.4.1 Patient selection 3 PEDIATRIC 3.1 Dosage Forms & Strengths 3.1.1 capsule 3.1.2 oral solution 3.2 Solid Tumors 3.3 Dosage Modifications 3.3.1 Dosage modifications for adverse reactions 3.3.1.1 BSA <1 m2 3.3.1.2 BSA ≥1 m2 3.3.2 Grade ≥3 adverse reactions 3.3.3 Strong CYP3A4 … Continue reading LARODX 100 (Larotrectinib)