- Details
- Description
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Packaging Size100t/Bottle
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Strength500mg
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CompositonVigabatrin
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TreatmentSeizures
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FormTablet
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BrandLuciViga
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Quantity Unit500mg*100T/Box
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ManufacturerLucius Pharmaceuticals (Lao) Co.,Ltd
About Vigabatrin
Vigabatrin is used alone or together with other medicines to treat refractory complex partial seizures in adults and children 2 years of age and older, and infantile spasms in children. It is used in patients who have already been treated with other medicines that did not work well. Vigabatrin is an anticonvulsant.
Partial Seizures
Indicated as adjunctive therapy for refractory complex partial seizures in patients who have inadequately responded to several seizure treatments and for whom the potential benefits of vigabatrin outweigh the risk of vision loss
500 mg PO q12hr initially, THEN increase by 500-mg increments qWeek to target dose of 1.5 g q12hr
No additional benefit shown with 6 g daily compared with 3 g daily; higher incidence of adverse effects associated with 6 g daily
Dosage Modifications
Renal impairment
- Mild (CrCl >50 to 80 mL/min): Decrease dose by 25%
- Moderate (CrCl >30 to 50 mL/min): Decrease dose by 50%
- Severe (CrCl >10 to 30 mL/min): Decrease dose by 75%
- Hemodialysis: Clearance not adequately studied
