Contents hide 1 About Acoramidis 1.1 Transthyretin Amyloid Cardiomyopathy 1.2 Dosage Modifications 1.2.1 Renal impairment 1.2.2 Hepatic impairment About Acoramidis Acoramidis is a near-complete (>90%) transthyretin stabilizer, developed to mimic the protective properties of the naturally occurring T119M mutation, to treat transthyretin amyloid cardiomyopathy.  Acoramidis is used to treat cardiomyopathy (enlarged and thickened heart muscle) of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM), to reduce death and hospitalization related to heart problems.  It is taken by mouth.The most common adverse reactions include diarrhea and upper abdominal pain. Transthyretin Amyloid Cardiomyopathy Indicated for cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM) in adults to reduce cardiovascular death and cardiovascular-related hospitalization … Continue reading LuciAcor (Acoramidis)