TreatmentBRCA mutations Breast cancer
ManufacturerPHOKHAM 2 PHARMACEUTICAL,LAOs PDR
Talazoparib, sold under the brand name Photalaz1,Talzenna, is an orally available poly ADP ribose polymerase (PARP) inhibitor developed by Pfizer for the treatment of advanced breast cancer with germline BRCA mutations. Talazoparib is similar to the first in class PARP inhibitor, olaparib. It was approved in October 2018, in the United States and June 2019, in the European Union for germline BRCA-mutated, HER2-negative locally advanced or metastatic breast cancer.
Why is this medication prescribed?
Talazoparib is used to treat certain types of breast cancer that has spread within the breast or to other areas of the body. Talazoparib is in a class of medications called poly (ADP-ribose) polymerase (PARP) inhibitors. It works by stopping or slowing the growth of cancer cells.
How should this medicine be used?
Talazoparib comes as a capsule to take by mouth. It is usually taken with or without food once a day. Take talazoparib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take talazoparib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the capsules whole; do not dissolve or open them.
If you vomit after taking talazoparib, do not take another dose. Continue your regular dosing schedule.
Your doctor may decrease your dose of talazoparib, or permanently or temporarily stop your treatment, if you experience certain side effects. Be sure to tell your doctor how you are feeling during your treatment with talazoparib.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What side effects can this medication cause?
Talazoparib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
loss of appetite
change in sense of taste