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LuciSelade (Seladelpar)

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Model Number：

RL362025060903
Brand Name：

LuciSelade
Origin：

Generic drug，Laos
Small Orders：

Small batches also available

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Poster

Details
Description

Packaging Size

30capsules/bottle
Strength

10mg
Compositon

Seladelpar
Treatment

Primary Biliary Cholangitis
Form

capslue
Brand

LuciSelade
Quantity Unit

10mg*30c/Box
Manufacturer

Lucius Pharmaceuticals (Lao) Co.,Ltd

Contents hide

1 About Seladelpar

1.1 Primary Biliary Cholangitis

1.2 Dosage Modifications

1.2.1 Coadministration with bile acid sequestrants

1.2.2 Renal impairment

1.2.3 Hepatic impairment

1.2.3.1 Decompensated cirrhosis

About Seladelpar

Seladelpar is a medication used for the treatment of primary biliary cholangitis. It is used as the lysine dihydrate salt. It is a peroxisome proliferator-activated receptor delta (PPARδ) receptor agonist.

Primary Biliary Cholangitis

Indicated for primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as monotherapy if unable to tolerate UDCA

10 mg PO qDay

Dosage Modifications

Coadministration with bile acid sequestrants

Administer seladelpar at least 4 hr before or 4 hr after taking bile acid sequestrants, or at the greatest possible interval

Renal impairment

Mild, moderate, or severe: No dosage adjustment recommended
ESRD on dialysis: Not studied

Hepatic impairment

Mild (Child-Pugh A): No dosage adjustment recommended
Decompensated cirrhosis
- Safety and efficacy not established; not recommended with decompensated cirrhosis (eg, ascites, variceal bleeding, hepatic encephalopathy)
- Monitor patients with cirrhosis for evidence of decompensation
- Consider discontinuing if progresses to moderate or severe impairment (Child-Pugh B or C)