BTROZI (Taletrectinib)

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  • Model Number:
    RL362025061203
  • Brand Name:
    达伯乐 (BTROZI)
  • Origin:
    Original invention from China
  • Small Orders:
    Small batches also available
  • Tags:
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Poster
  • Details
  • Description
  • Packaging Size
    33c/bottle
  • Strength
    0.2g
  • Compositon
    Taletrectinib
  • Treatment
    ROS1-positive non–small cell lung cancer
  • Form
    capsule
  • Brand
    达伯乐 (BTROZI)
  • Quantity Unit
    0.2g*33c/box
  • Manufacturer
    Innovent & Nuvation Bio

Taletrectinib is a potent, orally active, and next-generation selective ROS1/NTRK inhibitor. Taletrectinib potently inhibits recombinant ROS1, NTRK1, NTRK2, and NTRK3 with IC50s of 0.207, 0.622, 2.28, and 0.98 nM, respectively. Taletrectinib also inhibits ROS1 G2032R and other Crizotinib-resistant ROS1 mutants.

The FDA has approved taletrectinib (Ibtrozi) for the treatment of patients with locally advanced or metastatic, ROS1-positive non–small cell lung cancer

FDA approves taletrectinib for ROS1-positive non-small cell lung cancer


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