- Details
- Description
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Packaging Size90t/Bottle
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Strength50mg
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CompositonNirogacestat
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TreatmentDesmoid Tumors are a type of fibromatosis and related to sarcoma
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FormTablet
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BrandLuciNiro
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Quantity Unit50mg*90t/Box
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ManufacturerLucius Pharmaceuticals (Lao) Co.,Ltd
About Nirogacestat
Nirogacestat is an oral, gamma-secretase inhibitor approved to treat adults with progressing desmoid tumors that require systemic treatment. It works by blocking the abnormal protein that signals tumors to grow, helping to stop or slow their progression. Clinical trials showed significant improvements in progression-free survival and tumor response rates, though common side effects include diarrhea, ovarian toxicity, and electrolyte abnormalities.
Recommended Dosage
The recommended dosage of OGSIVEO is 150 mg administered orally twice daily until disease progression or unacceptable toxicity. Each 150 mg dose of OGSIVEO consists of three 50 mg tablets or one 150 mg tablet. OGSIVEO may be taken with or without food.
Instruct patients to swallow OGSIVEO tablets whole and not to break, crush, or chew prior to swallowing.
If a patient vomits or misses a dose, instruct the patient to take the next dose at its scheduled time.
